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Egg Donation

 Egg Donation is designed to assist women, who have specific reproductive problems, to have a baby. Many of these women have undergone premature ovarian failure, either due to natural cessation of ovarian function, or due to chemotherapy or radiotherapy. In addition, some women have ovaries that cannot be adequately stimulated for In Vitro Fertilization, while other women have transmissible genetic problems, which precludes the use of their own eggs.

Egg Donor Program

Egg Donation is designed to assist women, who have specific reproductive problems, to have a baby. Many of these women have undergone premature ovarian failure, either due to natural cessation of ovarian function, or due to chemotherapy or radiotherapy. In addition, some women have ovaries that cannot be adequately stimulated for In Vitro Fertilization, while other women have transmissible genetic problems, which precludes the use of their own eggs.

Egg donor screening

During the donation process recipient couples complete testing for infectious diseases, genetic screening, and other diagnostic testing. Couples also consult with our doctor familiar with issues relating to egg donation and assisted reproductive technologies. Recipient couples meet with an egg donor coordinator to discuss the donation process and the characteristics they are searching for in a donor. Egg donor coordinators search the donor database for matches and provide the couples with donor profiles containing medical history, family background, and personality profile.

Our egg donors will be dependable because of our intensive screening for sexual transmitted diseases including Anti-HIV, Anti-HCV, HBs-Ag, Anti-HBs, VDRL. In addition, they will be screened blood group, Rh group and Thalassemia.

Egg Donor Procedure Overview

Your initial step is to select a donor from our donor pool. Our medical staff then coordinates your cycle with that of the donor to obtain a fresh embryo transfer. Synchronization of cycles includes using a series of medications to facilitate a hospitable uterine environment for transfer of embryos. All viable eggs produced in a single donor cycle are fertilized with your partner's sperm, and all embryos belong to you. If there are more embryos than required for your transfer we can freeze the remaining embryos. The frozen embryos can be used for subsequent attempts at pregnancy whether or not your fresh transfer is successful. In general, any woman with a medical or genetic indication for using an egg donor can be a recipient, as long as there are no medical contraindications to pregnancy. Some patients look for gestational surrogacy co-operated with these egg donors because of their ovarian and uterine obstacles .

The Medical Schedule for recipient

If you use a Donor, the cycle starts once you have selected your egg donor. At this time we will also be starting the donor on medication to suppress her ovaries. When you have menstruation, we can coordinate your cycles. This can be done while you are still in your home country. It is similar to Surrogacy preparation, you will start using daily oral and/or weekly transdermal estrogen hormone to establish a healthy endometrial lining and the donor will begin the stimulation of her ovaries with stimulation hormone, FSH. When the follicles on her ovaries have reached a mature size (generally 10 -13 days from stimulation start) we will notify you that we are ready for the next step. At this time you see your doctor for an ultrasound to measure the thickness of your endometrial lining. You will then begin using post ovulated hormone, vaginal and/or oral progesterone supplementation to increase your progesterone levels in order to imitates the natural process of pregnancy. We will also schedule sperm collection on the day of egg retrieval, so you and your partner will need to be in our clinic at this time. In case the male could not be available on the egg retrieval day, sperm freezing process can be used prior to starting donor process.

Embryo Transfer

AThe day after egg retrieval and sperm collection we will communicate you with the retrieval result (ie, how many mature eggs have been retrieved) and the results of fertilization (how many viable embryos you have). Our doctor and you will discuss together that what is the proper number of embryos you wish to transfer and how many embryos you wish to store/freeze for later use. Normally, embryo transfer will be performed on day5 after retrieval. On the day of embryo transfer, we will confirm with you the number of embryos that you would like transferred – due to the possibility of multiple pregnancies we usually advise couples not to transfer more than 3 embryos. The transfer is performed in our transfer room and requires no special preparation on your part. Transfer of the embryos directly into the proper position of the endometrial lining in your uterus. This critical process is done under ultrasound guidance. You might feel only little discomfort and no anesthetic is required. After finishing transfer process, you will take 1-2 hours of rest in our clinic.

Pregnancy Test

10-14 days after the embryo transfer we will perform a serum (blood) pregnancy test. This can be performed at our clinic if you remain in Thailand or with your doctor when you return home. You should rest and relax for one-two days after the transfer but after that you can travel home. You will continue with vaginal progesterone and oral/transdermal estrogen until the pregnancy test. If the pregnancy test is negative you will discontinue all medications and will probably begin a period within the next week. If the pregnancy test is positive we will recheck your hormonal levels every week for 3 weeks. You must continue the estrogen and progesterone including injections for another 10 weeks (until 12 weeks gestation when the placenta will be supporting the pregnancy).